Author

Wen Yao

Rutgers, The State University of New JerseyORCID 0009-0003-8021-5545Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1

Frequent Co-Authors

Kelly A. Norris· 2 shared Luciano D'adamioiD· 2 shared Tao YiniD· 2 shared Lionel BreuillaudiD· 1 shared Simone P. Zehntner· 1 shared Siqiang ReniD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersNeuroscience

Kelly A. Norris

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 24, 2021

Familial Danish dementia young Knock-in rats expressing humanized APP and human Aβ show impaired pre and postsynaptic glutamatergic transmission

Tao Yin, Wen Yao, Kelly A. Norris, Luciano D'adamio

The paper investigates early pathogenic changes in young rats with the Danish mutation in Itm2b, showing altered glutamatergic synaptic function and human Aβ levels.

DOI 10.1101/2021.06.24.449787

ratexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 20, 2020

TNFα reduces inhibitory transmission in young Trem2R47H Sporadic Alzheimer rats before observable Aβ and brain pathology

Siqiang Ren, Lionel Breuillaud, Wen Yao…·Luciano D'adamio

The paper shows that the p.R47H TREM2 variant reduces GABAergic transmission in young Alzheimer rats, mediated by TNF-α, before Aβ accumulation and brain pathology.

DOI 10.1101/2020.08.20.256099

ratelectronic health records

𝕏 PostBluesky