Cell BiologyPLoS PathogensPeer-reviewed
Prion propagation is controlled by a hierarchical network involving the nuclear Tfap2c and hnRNP K factors and the cytosolic mTORC1 complex
Stefano Sellitto, Davide Caredio, Matteo Bimbati…·Adriano Aguzzi
The paper identifies TFAP2C as a genetic interactor of hnRNP K, showing their roles in mTOR metabolic regulation and a causal link to prion propagation.