Author

Jonah Lee

Beth Israel Deaconess Medical CenterORCID 0009-0004-1877-882XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

John G. ClohessyiD· 2 shared Taru E. MuraneniD· 2 shared Alex TokeriD· 1 shared Alexandra IndegliaiD· 1 shared Alissandra L. HillisiD· 1 shared Franziska Michor AiD· 1 shared Howard H. Yang· 1 shared Isabella Ranieri· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

John G. ClohessyORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 24, 2026

Metabolic-epigenetic coupling between leucine catabolism and glycolysis drives CDK4/6 inhibitor resistance

Michael UJ Oliphant, Klarisa Norton, Kiran Kurmi…·Senthil K. Muthuswamy

This study identifies a metabolic-epigenetic mechanism linking leucine catabolism to glycolysis that drives resistance to CDK4/6 inhibitors in ER+ breast cancer.

DOI 10.64898/2026.09.23.752387

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintSep 22, 2026

MAPK signaling links BRD2 chromatin occupancy to PI3K/AKT inhibitor sensitivity

Josefina Mendez, Simone Bruno, Alexandra Indeglia…·Alex Toker

This study identifies BRD2 as a co-targetable vulnerability with PI3K/AKT inhibitors in breast cancer, showing that BRD2 phosphorylation is required for chromatin binding and that targeting BRD2 enhances drug efficacy.

DOI 10.64898/2026.09.21.753236

humanstatistical model

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