Author

Michael UJ Oliphant

Beth Israel Deaconess Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Senthil K. MuthuswamyiD· 2 shared Ahmed YoussefiD· 1 shared Andrew EmiliiD· 1 shared Brian RaughtiD· 1 shared Carl A. White· 1 shared Christopher S. CheniD· 1 shared Dante BolzaniD· 1 shared Dima KozakoviD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Senthil K. MuthuswamyORCID

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2 papers

Recent·Most cited

Metabolic-epigenetic coupling between leucine catabolism and glycolysis drives CDK4/6 inhibitor resistance

Michael UJ Oliphant, Klarisa Norton, Kiran Kurmi, Howard H. Yang, Shakchhi Joshi, Jonah Lee, Nina Kozlova, Taru E. Muranen, John G. Clohessy, Marcia C. Haigis, Senthil K. Muthuswamy

This study identifies a metabolic-epigenetic mechanism linking leucine catabolism to glycolysis that drives resistance to CDK4/6 inhibitors in ER+ breast cancer.

bioRxiv · Sep 24, 2026 · PreprintCancer Biology

A multi-tiered map of EMT defines major transition points and identifies vulnerabilities

Indranil Paul, Dante Bolzan, Ahmed Youssef, Keith A. Gagnon, Heather Hook, Gopal Karemore, Michael UJ Oliphant, Weiwei Lin, Qian Liu, Sadhna Phanse, Carl A. White, Dzmitry Padhorny, Sergei Kotelnikov, Guillaume P. Andrieu, Christopher S. Chen, , Andrew Emili

The paper maps EMT transitions through multi-omic profiling, identifies key regulatory factors, and reveals discordance between molecular layers in human mammary epithelial cells.

bioRxiv · Jun 1, 2021 · PreprintSystems Biology