Author
Harvard UniversityORCID 0000-0002-1345-0196Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Michael UJ Oliphant, Klarisa Norton, Kiran Kurmi…·Senthil K. Muthuswamy
This study identifies a metabolic-epigenetic mechanism linking leucine catabolism to glycolysis that drives resistance to CDK4/6 inhibitors in ER+ breast cancer.
Eva Nývltová, Paola Manara, Ahram Ahn…·Antoni Barrientos
This study shows mitochondrial translation is sensitive to ATP synthase activity, with matrix GTP availability identified as a key constraint.
Mohammad Adeel Zafar, Charlotte Nicole Hill Machado, Jyotirmaya Behera…·Louis‐Marie Charbonnier
This study shows glutamine supports autoimmune disease in Foxp3 deficiency by fueling biosynthetic pathways in T and B cells, with distinct roles in cytokine production and autoantibody formation.
Peter Georgiev, Sheila E. Johnson, Kiran Kurmi…·Arlene H. Sharpe
Asmita Pathak, Sravya Palavalasa, Bruno Colon…·Defne Bayık
This study shows GABA receptor B signaling promotes GBM growth in females through immune mechanisms, with sex-specific effects on survival and treatment outcomes.
Zuen Ren, Tiziano Bernasocchi, Kiran Kurmi…·Leif William Ellisen
This study identifies SIRT5-induced metabolic changes as a driver of chemoresistance in TNBC and reveals ATR checkpoint dependence as a therapeutic vulnerability.