Author

Klarisa Norton

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adam C. WeineriD· 1 shared Alicia Pollaci· 1 shared Andrew McPhersoniD· 1 shared Caroline BariliD· 1 shared Cathy Liu· 1 shared Ciara H. O’FlanaganiD· 1 shared Daniel LaiiD· 1 shared Deborah A. R. DilloniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Adam C. WeinerORCID

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2 papers

Recent·Most cited

Metabolic-epigenetic coupling between leucine catabolism and glycolysis drives CDK4/6 inhibitor resistance

Michael UJ Oliphant, Klarisa Norton, Kiran Kurmi, Howard H. Yang, Shakchhi Joshi, Jonah Lee, Nina Kozlova, Taru E. Muranen, John G. Clohessy, Marcia C. Haigis, Senthil K. Muthuswamy

This study identifies a metabolic-epigenetic mechanism linking leucine catabolism to glycolysis that drives resistance to CDK4/6 inhibitors in ER+ breast cancer.

bioRxiv · Sep 24, 2026 · PreprintCancer Biology

Luminal breast epithelial cells from wildtype and BRCA mutation carriers harbor copy number alterations commonly associated with breast cancer

Marc J. Williams, Michael U. J. Oliphant, Vinci Au, Cathy Liu, Caroline Baril, Ciara H. O’Flanagan, Daniel Lai, Sean Beatty, Michael Van Vliet, Jacky Chun Hei Yiu, Lauren O’Connor, Walter L. Goh, Alicia Pollaci, Adam C. Weiner, Diljot S. Grewal, , Samuel A. J. R. Aparicio

The paper analyzes copy number alterations in breast epithelial cells from BRCA mutation carriers and wildtype individuals, finding lineage-specific CNAs that mirror cancer genomes.

Nature Genetics · Nov 20, 2024Peer-reviewedCancer Biology