Author

Cassandra A. Chartier

Columbia UniversityORCID 0009-0004-2474-9937Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew C. JohnsiD· 1 shared Ann E. McDermottiD· 1 shared Anne E. van VlimmereniD· 1 shared D. A. KeedyiD· 1 shared Marko JovanovićiD· 1 shared Neel H. ShahiD· 1 shared Virgil A. WoodsiD· 1 shared Yunyao XuiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Andrew C. JohnsORCID

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1 paper

Recent·Most cited

BiochemistryProtein SciencePeer-reviewedDec 26, 2024

Allosteric regulation of the tyrosine phosphatase PTP1B by a protein-protein interaction

Cassandra A. Chartier, Virgil A. Woods, Yunyao Xu…·Neel H. Shah

This paper shows that Grb2 binding to PTP1B allosterically enhances its catalytic activity through structural changes, revealing a new regulatory mechanism for PTP1B in cell signaling.

13 citations

humanproteomics