Author

Sharon Wu

Caris Life Sciences (United States)ORCID 0009-0004-3451-2247Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Sharon Wu1 paper · Boston Children's Hospital

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Alejandro Recio‐BoilesiD· 1 shared Alex Patrick FarrelliD· 1 shared Amber N. ClementsiD· 1 shared An Nguyen· 1 shared Andrea L. CasillasiD· 1 shared Anne E. CressiD· 1 shared Arun A. Chandrakumar· 1 shared Ben DoroniD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Alejandro Recio‐BoilesORCID

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3 papers

Recent·Most cited

EGFR amplification and PI3K pathway mutations identify a subset of breast cancers that synergistically respond to EGFR and PI3K inhibition

David John Wisniewski, Donna M. Voeller, Yonit A. Addissie, Sachin Kumar Deshmukh, Sharon Wu, Maryam B. Lustberg, Darawalee Wangsa, Danny Wangsa, Kerstin Heselmeyer‐Haddad, Yoshimi Endo Greer, George W. Sledge, Stanley Lipkowitz

Oncogene · Nov 25, 2025Peer-reviewedCancer Biology

Reconstructing tumor evolution without chromosomal instability reveals in vivo determinants of therapeutic response

Ruhollah Moussavi-Baygi, Matthew J. Ryan, Woogwang Sim, Samuel B Hoelscher, Valbona Luga, Arun A. Chandrakumar, Lore Hoes, Junghwa Cha, Young Sun Lee, Katelyn Herm, Ben Doron, Danika Bakke, Sharon Wu, C.K. Cornelia Ding, Bradley A. Stohr, , Rohit Bose

This study develops an in vivo platform called SETs to reconstruct tumor evolution without chromosomal instability, identifying therapeutic response determinants in prostate cancer.

bioRxiv · Mar 17, 2025 · PreprintCancer Biology

Inhibition of PIM kinase in tumor associated macrophages suppresses inflammasome 1 activation and sensitizes prostate cancer to immunotherapy

Amber N. Clements, Andrea L. Casillas, Caitlyn E. Flores, Hope Liou, Rachel K. Toth, Shailender Singh Chauhan, Kai Sutterby, Sachin Kumar Deshmukh, Sharon Wu, Joanne Xiu, Alex Patrick Farrell, Milan Radovich, Chadi Nabhan, Elisabeth I. Heath, Rana R. McKay, , Noel A. Warfel

This study shows that inhibiting PIM kinases in tumor-associated macrophages reduces inflammasome activation and improves response to immunotherapy in prostate cancer.

Cancer Immunology Research · Feb 21, 2025Peer-reviewedCancer Biology