Author

Alexandra N. Wolff

Harvard UniversityORCID 0009-0004-4209-4129Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Adele MucciiD· 1 shared Amanda A. BouffardiD· 1 shared Cassidy Ho· 1 shared Justin H. PaekiD· 1 shared Marcela Valderrama MausiD· 1 shared Matthew J. PaszekiD· 1 shared Sangwoo ParkiD· 1 shared Trisha R. BergeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

Adele MucciORCID

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1 paper

Recent·Most cited

BioengineeringbioRxivPreprintSep 27, 2026

Engineering CAR-T cells to remodel the mucin-rich cancer cell glycocalyx

Sangwoo Park, Cassidy Ho, Alexandra N. Wolff…·Marcela Valderrama Maus

This study engineers CAR-T cells to secrete KLK5, a protease that remodels the mucin-rich glycocalyx, enhancing CAR-T cell function and tumor control in xenograft models.

DOI 10.64898/2026.09.25.754490

humanproteomics

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