Cancer BiologyOncogenesisPeer-reviewed
Targeting Pregnane X Receptor with a Potent Agonist-Based PROTAC to Delay Colon Cancer Relapse
Lucile Bansard, Guillaume Laconde, Vanessa Delfosse…·Jean‐Marc Pascussi
This study designs and tests a PXR agonist-based PROTAC (JMV7048) that degrades PXR in cancer cells, reducing chemoresistance and delaying colon cancer relapse.
8 citations