Author

Jamie Lee Roos

Amsterdam UMCORCID 0009-0004-4884-7726Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Arnon Philip KateriD· 2 shared Eric ElderingiD· 2 shared Marco Vincent HaselageriD· 2 shared Aldo JongejaniD· 1 shared Caitrin CruddeniD· 1 shared Claudia V. Perez AlmeriaiD· 1 shared Danial LashgariiD· 1 shared Daphne JurriensiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Arnon Philip KaterORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 3, 2026

Single-cell characterization of 3D CLL spheroid model that recapitulates lymph node microenvironment-driven phenotypes and in vivo drug responses to ibrutinib

Marco V Haselager, Danial Lashgari, Aldo Jongejan…·Eric Eldering

The paper uses a 3D CLL spheroid model to study how lymph node microenvironmental signals influence CLL cell phenotypes and drug responses to ibrutinib.

DOI 10.64898/2026.10.31.763314

humanscRNA-seq

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BiochemistryProceedings of the National Academy of SciencesPeer-reviewedJun 11, 2025

Disruption of basal CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms

Simon Mobach, Nick D. Bergkamp, Ziliang Ma…·Raimond Heukers

This study shows that disrupting CXCR4 oligomers in lymphoid cancers reduces migration, survival signaling, and tumor growth, while sensitizing cells to venetoclax.

6 citations

humanproteomics

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