Author

Garrett Ruth

University of WashingtonORCID 0009-0004-4974-0410Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

David A. BakeriD· 2 shared Rashmi RavichandraniD· 2 shared Alka JaysiD· 1 shared Anne PinkiD· 1 shared Brendan Larsen· 1 shared Brian CoventryiD· 1 shared Cameron StewartiD· 1 shared Christopher C. BroderiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

David A. BakerORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintSep 17, 2026

Computational design of potent, broadly neutralizing anti-Nipah virus and Hendra virus miniproteins

Jeremiah Nelson Sims, Risako Gen, Kaitlin R. Sprouse…·David A. Baker

This paper computationally designs thermostable miniproteins that neutralize Nipah and Hendra viruses with subnanomolar affinity and potent in vitro antiviral activity.

DOI 10.64898/2026.09.14.751546

protein structureexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintMay 2, 2026

Integrin-independent Tie2 activation using de novo designed proteins

Clara McCurdy, Yan Ting Zhao, Saurav Kumar…·Hannele Ruohola‐Baker

This paper designs a de novo Tie2 binder that activates the Angiopoietin-Tie2 pathway without integrin engagement, showing improved therapeutic potential in a mouse model of ARDS.

DOI 10.64898/2026.05.01.718274

mousedeep learning

𝕏 PostBluesky