Author

Barbara Krystyna Stepien

Technische Universität DresdenORCID 0009-0004-5620-0252Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anja Krüger· 2 shared Ben WielockxiD· 2 shared Peter MirtschinkiD· 2 shared Stephen Ariyeloye· 2 shared Ali El‐ArmoucheiD· 1 shared Anupam Sinha· 1 shared Cagdas Ermis· 1 shared Deepika WattsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMolecular Biology

Anja Krüger

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 26, 2026

HIF-1α coordinates adrenal steroidogenesis through direct transcriptional control and regulation of miRNA biogenesis

Barbara Krystyna Stepien, Anupam Sinha, Stephen Ariyeloye…·Ben Wielockx

The paper identifies HIF-1's role in regulating adrenal steroidogenesis through direct transcriptional control and miRNA biogenesis, revealing hypoxia's impact on miRNA-processing genes.

DOI 10.64898/2026.02.24.707817

mouseChIP-seq

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Molecular BiologyCell Communication and SignalingPeer-reviewedFeb 13, 2025

HIF1α controls steroidogenesis under acute hypoxic stress

Stephen Ariyeloye, Deepika Watts, Mangesh T. Jaykar…·Ben Wielockx

This study investigates how HIF1α regulates steroidogenesis under acute hypoxia using cell lines, ex vivo models, and mice, finding HIF1α-dependent miRNA regulation and translational control of steroidogenic enzymes.

8 citationstop 4%

mousebulk RNA-seq

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