Harrison H. Truscott

The paper investigates how actin-membrane interface stress regulates Arp2/3-branched actin density during lamellipodial protrusion in response to extracellular conditions.

The paper quantifies fibroblast migration by analyzing force generation, cell shape, and motion, identifying discrete migratory states that are influenced by cytoskeletal organization.

This study shows that local activation of PLC-γ1 via optogenetic tools can direct cell motility, revealing its role in chemotaxis beyond mere signaling.

This paper examines whether diffusion models can extract physics-like energies for protein docking, finding they can recover energy funnels comparable to Rosetta in 9 out of 25 cases.

This study measures cellular traction forces during confined migration through tunable microscale geometries, revealing that softer constrictions cause greater nuclear deformation due to internal contractile forces.