Author

Jesslyn Zhou

National University of SingaporeORCID 0009-0004-8645-5192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1

Frequent Co-Authors

Bryan Y.L. NgiD· 2 shared Haoqing SheniD· 2 shared Jian Han· 2 shared Ka Wai Leong· 2 shared Larry NgiD· 2 shared Sze Jing TangiD· 2 shared Vanessa Hui En NgiD· 2 shared Vincent TanoiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Bryan Y.L. NgORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMay 29, 2026

Intron 13 retention expands the ADAR1 isoform repertoire to rewire PKR signaling and promote tumorigenesis

Bryan Y.L. Ng, Jesslyn Zhou, Sze Jing Tang…·Peng Chen

The paper identifies novel ADAR1 isoforms generated by intron retention that sequester dsRNA to inhibit PKR and promote tumorigenesis in colorectal cancer.

DOI 10.64898/2026.05.26.727889

humanbulk RNA-seq

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Cell BiologybioRxivPreprintJan 7, 2026

Mitochondrial dsRNA: A Hidden Source of Immunogenic RNA in ADAR1 Deficiency

Haoqing Shen, Vincent Tano, Jian Han…·Leilei Polly Chen

This study identifies mitochondrial dsRNA as a major endogenous dsRNA source in ADAR1 deficiency and proposes a mechanism linking ADAR1 dysfunction to immune activation.

DOI 10.64898/2026.01.06.698045

humanmouse

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