Van N. Pham

This study identifies Shoc2 as a critical regulator of lymphangiogenesis by suppressing mTORC1-mediated IFN responses, leading to lymphatic vasculature loss and cellular senescence.

This study identifies and characterizes specialized endothelial cells in zebrafish gills that resemble mammalian lung aerocytes, using single-cell RNA sequencing and advanced imaging techniques.

This paper characterizes the zebrafish meninges using single-cell transcriptomics, identifying a novel cell type essential for brain development.

The paper identifies a new external immune organ in zebrafish, the axillary lymphoid organ, suitable for live imaging of immune cell dynamics.

This study shows that LIC1 and RILPL1/2 restrict angiogenesis by promoting VEGFR2 degradation, and their disruption increases angiogenesis through enhanced Rab11-mediated recycling.

The paper introduces a zebrafish transgenic line to profile endothelial cell translatomes in vivo, revealing novel genes and expression signatures across adult organs.

The paper identifies a meningeal lymphatic network in zebrafish, comparable to mammals, and demonstrates its function in draining brain interstitial fluid and immune cell trafficking.

This study identifies miR-204 as a key regulator of lymphangiogenesis, showing its role in lymphatic vessel formation and its interaction with NFATC1.