Author

Niels J. Rinzema

University Medical Center UtrechtORCID 0009-0005-1139-9365Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

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Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Anna-Karina FelderiD· 1 shared Christian Valdes‐QuezadaiD· 1 shared Konstantinos Sofiadis· 1 shared Marjon J.A.M. Verstegen· 1 shared Peter H.L. KrijgeriD· 1 shared Ruiqi HaniD· 1 shared Sjoerd J. D. TjalsmaiD· 1 shared Stefan van der Elst· 1 shared

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1 shared paperMolecular Biology

Anna-Karina FelderORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintOct 5, 2021

Building regulatory landscapes: enhancer recruits cohesin to create contact domains, engage CTCF sites and activate distant genes

Niels J. Rinzema, Konstantinos Sofiadis, Sjoerd J. D. Tjalsma…·Wouter L. de Laat

This study shows enhancers recruit cohesin to form chromatin domains, engage CTCF sites, and activate distant genes, with transcription factors and mediator required for all distances but cohesin specifically for long-range activation.

8 citations

ChIP-seqDNA methylation

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