Author

Serwah A. Danquah

Broad InstituteORCID 0009-0005-1174-0105Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Assay:CRISPR screen· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

Ralda NehmeiD· 3 shared Samouil L. FarhiiD· 3 shared Byunguk KangiD· 2 shared Ernest FraenkeliD· 2 shared Matthew Joseph LeventhaliD· 2 shared Aiping JiangiD· 1 shared Brian ClearyiD· 1 shared Brooke SimontoniD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersSystems Biology

Ralda NehmeORCID

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3 papers

Recent·Most cited

Systems BiologyNature CommunicationsPeer-reviewedMay 20, 2025

An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration

Matthew Joseph Leventhal, Camila A. Zanella, Byunguk Kang…·Ernest Fraenkel

This study integrates multi-omics data from Drosophila and human Alzheimer's disease models to identify pathways involved in neurodegeneration.

28 citationstop 1%

Drosophilahuman

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GenomicsCellPeer-reviewedMar 12, 2025

Simultaneous CRISPR screening and spatial transcriptomics reveals intracellular, intercellular, and functional transcriptional circuits.

Loïc Binan, Aiping Jiang, Serwah A. Danquah…·Samouil L. Farhi

This paper introduces Perturb-FISH, a method combining spatial transcriptomics and CRISPR screening to study transcriptional circuits, showing intracellular and intercellular effects in immune and neurological contexts.

139 citationstop 1%

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NeurosciencebioRxivPreprintFeb 19, 2025

CellPHIE: Integrating Pathway Discovery With Pooled Profiling of Perturbations Uncovers Pathways of Huntington's Disease, Including Genetic Modifiers of Neuronal Development and Morphology

Byunguk Kang, Michael A. Murphy, Christopher Ng…·Ernest Fraenkel

The paper integrates pathway discovery with pooled genetic perturbation to identify modifiers of Huntington's disease, revealing genes involved in neuronal development and morphology.

DOI 10.1101/2025.02.19.639023

humanCRISPR screen

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