Author

Andrea Pérez Arévalo

Icahn School of Medicine at Mount SinaiORCID 0009-0005-1498-5423Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anna BrightiD· 2 shared Joel BlanchardiD· 2 shared Aisha SatiiD· 1 shared Alison GoateiD· 1 shared Ana C. PereiraiD· 1 shared Ashley HarlockiD· 1 shared Braxton Riley SchuldtiD· 1 shared Diede W. M. BroekaartiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Anna BrightORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 6, 2026

ATP13A2 Loss of Function-Driven Polyamine Dysregulation Induces SAM Depletion and Epigenetic Astrocyte Toxicity

Elena Coccia, Gustavo Morrone Parfitt, Sundas Ijaz…·Joel Blanchard

The paper shows ATP13A2 loss of function disrupts polyamine metabolism, leading to SAM depletion and epigenetic astrocyte toxicity, which contributes to Parkinson's disease.

1 citation

humanmouse

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NeurosciencebioRxivPreprintSep 4, 2025

APOE4 promotes cerebrovascular fibrosis and amyloid deposition via a pericyte-to-myofibroblast transition

Braxton Riley Schuldt, Dominic Haworth-Staines, Andrea Pérez Arévalo…·Joel Blanchard

This study identifies APOE4-driven pericyte-to-myofibroblast transition in cerebrovascular disease, leading to fibrosis and amyloid deposition, and shows TGF-β inhibition can reverse these effects.

2 citations

humanscRNA-seq

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