Author

Payal Arora

University of PittsburghORCID 0009-0005-1512-2777Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:yeast· 4 Assay:DNA methylation· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Craig D. KaplaniD· 4 shared Amber J. LaPerutaiD· 1 shared Brittany R. McVicar· 1 shared Bryce E. NickelsiD· 1 shared Chenxi QiuiD· 1 shared David A. BrowiD· 1 shared Emily M. Pavlovic· 1 shared Indranil MalikiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersMolecular Biology

Craig D. KaplanORCID

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4 papers

Recent·Most cited

Molecular BiologyGeneticsPeer-reviewedFeb 5, 2026

Genetic dissection of transcription start site selection by RNA polymerase II in Saccharomyces cerevisiae

Payal Arora, Kieran F Brennan, Marcie H. Warner, Craig D. Kaplan

The paper identifies mutants affecting transcription start site selection in yeast by analyzing promoter scanning mechanisms and their genetic reporters.

1 citation

yeastDNA methylation

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Molecular BiologybioRxivPreprintNov 5, 2025

RNA polymerase II-TFIIE-TFIIH interface functions in transcription start site selection in Saccharomyces cerevisiae

Pratik Basnet, Yunye Zhu, Irina O. Vvedenskaya…·Craig D. Kaplan

The paper investigates how the TFIIH-Pol II-TFIIE interface influences promoter scanning and TSS selection in yeast by analyzing genetic mutants and TSS sequencing data.

DOI 10.1101/2025.11.05.686797

yeaststatistical model

𝕏 PostBluesky

Molecular BiologyGeneticsPeer-reviewedOct 22, 2025

Substitutions in RNA-binding protein Hrp1 map a potential interaction surface with the yeast RNA polymerase II elongation complex

Moyao Wang, Payal Arora, Craig D. Kaplan, David A. Brow

The paper identifies Hrp1 as an RNAP II anti-termination factor and shows specific substitutions in Hrp1 and Rpb3 affect termination by altering protein interactions.

3 citations

yeastexperimental assay

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedDec 29, 2023

Thiolutin has complex effects in vivo but is a direct inhibitor of RNA Polymerase II in vitro

Chenxi Qiu, Payal Arora, Indranil Malik…·Craig D. Kaplan

This study investigates thiolutin's mode of action, showing it directly inhibits RNA Polymerase II in vitro but has complex in vivo effects involving oxidative stress and metal interactions.

20 citations

yeastexperimental assay

𝕏 PostBluesky