Quanhui Dai

This paper shows that Notch dimerization is essential for vascular integrity and that NDD mice exhibit environmental sensitivity and vascular defects.

The paper shows that Notch dimerization is crucial for intestinal homeostasis, with HDAC2 activity modulating Notch function in intestinal stem cells.

This paper develops synthetic agonists and antagonists for Wnt/β-catenin signaling to enhance organoid growth and inhibit cancer xenografts.

This study shows that Notch dimerization is critical for intestinal homeostasis and immune responses, with mite infestation worsening related phenotypes and triggering lymphoma in mutant mice.