Author

Meina Cai

Mayo ClinicORCID 0009-0005-2079-1000Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Danielle Marie CarlsoniD· 2 shared Rory L. SmootiD· 2 shared Sumera Irie IlyasiD· 2 shared Akhilesh PandeyiD· 1 shared Alexander L. TichoiD· 1 shared Amro M. AbdelrahmaniD· 1 shared Anna Splinter· 1 shared Binbin LiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Danielle Marie CarlsonORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 20, 2026

ESCRT-dependent YAP degradation by AKT blockade overcomes adaptive resistance to RAS(ON) inhibition in pancreatobiliary cancer

Jack W. Sample, Enis Özmert, Brandon A. Wilbanks…·Rory L. Smoot

This study identifies AKT as a regulator of YAP stability and shows that AKT inhibition triggers ESCRT-dependent YAP degradation, enhancing the efficacy of RAS inhibition in pancreatobiliary cancers.

DOI 10.64898/2026.10.18.759975

mouseproteomics

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Cancer BiologybioRxivPreprintJun 25, 2026

Therapy-induced senescent-like cancer cells drive macrophage-mediated immunosuppression in cholangiocarcinoma

Binbin Li, Jingchun Yang, Meina Cai…·Sumera Irie Ilyas

This study identifies therapy-induced senescent-like cancer cells as drivers of immunosuppression in cholangiocarcinoma by promoting macrophage-mediated suppression of CD8+ T cells.

DOI 10.64898/2026.06.24.734341

humanmouse

𝕏 PostBluesky