GenomicsbioRxivPreprint
Isoform-level resolution in single-cell CRISPR screens reveals hidden functional consequences of gene perturbation
Nathanael Andrews, Josie Gleeson, Jasper Panten…·Tuuli Lappalainen
This paper evaluates isoform-level resolution in single-cell CRISPR screens using long-read sequencing, finding that it captures splicing changes missed by gene-level analysis.
DOI 10.64898/2026.07.09.737410