Juan-Felipe Perez-Correa

This study identifies co-regulated DNA methylation patterns in leukemia and shows their presence in other cancer types, suggesting non-random, network-based epigenetic regulation.

This study shows that the level of myeloid skewing in blood correlates with biological aging and disease in mice and humans.

The paper introduces a weighted 2D-kernel density estimation method for epigenetic age prediction, achieving similar accuracy to existing clocks and providing variation scores linked to mortality risk.

This study shows that epigenetic editing at age-associated CpGs can modulate the epigenetic aging landscape, affecting epigenetic clocks and inducing non-random bystander modifications.

The paper develops an epigenetic clock for mice using age-associated CpGs conserved between mouse strains and humans, showing high correlation with chronological age.