Author

Vadim Sakk

Universität UlmORCID 0000-0001-5797-5851Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Hartmut GeigeriD· 4 shared Ani GrigoryaniD· 2 shared Wolfgang WagneriD· 2 shared Yi ZhengiD· 2 shared Alejandro Gracia-Garcia· 1 shared Ander IzetaiD· 1 shared Andrea JaenschiD· 1 shared Antigoni Karavelaki· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersCell Biology

Hartmut GeigerORCID

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 28, 2026

An aged human bone marrow mesenchymal niche causes impaired function of human hematopoietic stem cells under regeneration-induced stress

Ani Grigoryan, Ruba Abdelrahman, Wong Sik Seo…·Paul Emile Bourgine

This study shows that aged human bone marrow mesenchymal stromal cells impair hematopoietic stem cell function under regeneration stress by promoting myeloid bias.

DOI 10.64898/2026.10.27.762262

humanexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintJan 22, 2026

The extent of myeloid skewing in blood is a biomarker of biological aging in mice and humans

Julian Niemann, Selina Stahl, Vadim Sakk…·Mona Vogel

This study shows that the level of myeloid skewing in blood correlates with biological aging and disease in mice and humans.

DOI 10.64898/2026.01.20.700344

mousehuman

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Developmental BiologyEMBO ReportsPeer-reviewedOct 18, 2021

A Cdc42-Borg4-Septin 7 axis regulates HSCs polarity and function

Ravinder Kandi, Katharina Senger, Ani Grigoryan…·Hartmut Geiger

This study identifies a Cdc42-Borg4-Sep7 axis that regulates HSC polarity and function by controlling the polar distribution of these proteins and affecting engraftment potential and LMPP frequency.

31 citations

mouseexperimental assay

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GenomicseLifePeer-reviewedAug 24, 2018

Epigenetic Age-Predictor for Mice based on Three CpG Sites

Yang Han, Monika Eipel, Julia Franzen…·Wolfgang Wagner

This study develops a three-CpG site-based epigenetic age predictor for mice using DNA methylation data, showing it can accurately estimate chronological age in blood samples.

60 citations

mouseDNA methylation

𝕏 PostBluesky