Cancer BiologyJCI InsightPeer-reviewed
Regulation of fatty acid delivery to metastases by tumor endothelium
Deanna N. Edwards, Shan Wang, Kelby M. Kane…·Jin Chen
This study identifies a mechanism by which tumor endothelium regulates fatty acid delivery to metastases, showing that mTORC1 inhibition in endothelial cells reduces metastatic disease by impairing T cell fatty acid uptake.
8 citations