Zeal Jinwala

This study identifies sex-specific genetic loci and correlations for alcohol use behaviors and their comorbidities using genome-wide association studies.

This study investigates genetic predictors of inpatient opioid exposure after knee or hip surgery using EHR and genotype data from 27,896 individuals across three ancestries, finding no genome-wide significant loci.

This study identifies 343 genetic loci for chronic pain in 1.2 million individuals, revealing pleiotropy with psychiatric disorders and brain structures.

The paper integrates HiTOP and RDoC frameworks to identify shared and distinct biological mechanisms of externalizing and internalizing psychopathology using multi-omics approaches.

The paper uses genomic structural equation modeling to identify the genetic architecture of externalizing and internalizing psychopathology, finding a moderate genetic correlation and shared causal variants.

The paper uses polygenic scores to analyze pleiotropy between psychiatric, medical, and substance use disorders in a deeply phenotyped sample, finding extensive genetic overlap with substance use phenotypes.

This paper combines transdiagnostic and disorder-level GWAS to enhance genetic risk profiles for psychiatric disorders in multi-ancestry samples, identifying novel SNPs and shared genetic variance.

This study performs a multi-ancestry meta-analysis of tobacco use disorder using electronic health records, identifying 88 risk loci and 461 potential risk genes, and linking TUD to various health outcomes.