Zhijian Ji

The paper identifies ERGU-1 as a conserved antioxidant protein at ER membranes using AlphaFold2 and functional screens in C. elegans, showing its role in H2O2 detoxification and antioxidant defense.

The paper describes a reversible form of suspended animation in C. elegans induced by high population density and identifies molecular mechanisms regulating its induction and termination.

The paper introduces GENTIS, a genetically encoded ionic-stress sensor, and shows that proton accumulation drives sleep in C. elegans through v-ATPase inhibition and membrane disassembly.

This study shows visible light affects behavioral memory and gene expression in C. elegans through a non-visual pathway involving cyp-14A5 and bZIP transcription factors.