Author

Yanbo Chen

Yale UniversityORCID 0009-0005-6754-4525Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Research Focus:spatial domain detection· 2 Assay:ChIP-seq· 1 Organism:human· 1

Frequent Co-Authors

Siyuan S. WangiD· 3 shared Shengyan JiniD· 2 shared Yubao ChengiD· 2 shared Ailin Han· 1 shared Andrew XiaoiD· 1 shared Biao CaiiD· 1 shared David G. GonzaleziD· 1 shared Dennis P. MayiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersGenetics

Siyuan S. WangORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintJun 13, 2025

Non-disruptive 3D profiling of combinations of epigenetic marks in single cells

Yanbo Chen, Jonathan S. D. Radda, Myles H. Alderman…·Siyuan S. Wang

This paper introduces Epi-PHR, a non-disruptive method for single-cell spatial epigenetic profiling, revealing region-specific epigenetic profiles and allele-specific chromatin states.

5 citations

mouseChIP-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintMar 6, 2025

Sequencing-free whole genome spatial transcriptomics at molecular resolution in intact tissue

Yubao Cheng, Shengyuan Dang, Yuan Zhang…·Siyuan S. Wang

This paper introduces RAEFISH, a spatial transcriptomics technology that achieves whole-genome coverage and single-molecule resolution in intact tissues, enabling comprehensive analysis of RNA localization and cell interactions.

4 citations

humanmouse

𝕏 PostBluesky

GeneticseLifePeer-reviewedMar 7, 2023

Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo

Dennis P. May, Sangwon Yun, David G. Gonzalez…·Valentina Greco

The paper uses live imaging to study chromatin compaction and transcriptional dynamics during stem cell differentiation in live mouse epidermis, showing that chromatin changes follow transcriptional activity.

29 citations

mouseimaging

𝕏 PostBluesky