Developmental BiologybioRxivPreprint
Single-cell proteomics of pre-implantation mouse embryos uncovers distinct asymmetry of certain proteins among early blastomeres
Yuan Yuan, Mo Hu, Yinghui Zheng…·Xiaoliang Sunney Xie
The paper uses single-cell proteomics to show protein asymmetry in mouse blastomeres, independent of RNA expression, revealing a new mechanism for early cell fate determination.
DOI 10.1101/2024.09.28.614398