Author

Chao Yao

Shanghai Institute of Nutrition and Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Bahram NamjouiD· 2 shared Guojun HouiD· 2 shared Hong XuiD· 2 shared Huihua DingiD· 2 shared Jianyang MaiD· 2 shared John B. HarleyiD· 2 shared Leah Claire KottyaniD· 2 shared Matthew T. WeirauchiD· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Bahram NamjouORCID

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3 papers

Recent·Most cited

A systematic evaluation revealed that detecting translated non-canonical ORFs from ribosome profiling data remains challenging

Tianyu Lei, Yue Chang, Chao Yao, Hong Zhang

The paper evaluates four methods for detecting translated non-canonical ORFs from Ribo-Seq data and finds they have low precision and accuracy, especially for ORFs with near-cognate start codons.

Journal of genetics and genomics/Journal of Genetics and Genomics · Sep 4, 2023Peer-reviewedGenomics

CRISPRa screen on a genetic risk locus shared by multiple autoimmune diseases identifies a dysfunctional enhancer that affects IRF8 expression through cooperative lncRNA and DNA methylation machinery

Tian Zhou, Xinyi Zhu, Zhizhong Ye, Yongfei Wang, Chao Yao, Ning Xu, Mi Zhou, Jianyang Ma, Yuting Qin, Yiwei Shen, Yuanjia Tang, Zhihua Yin, Hong Xu, Yutong Zhang, Xiaoli Zang, , Nan Shen

The paper identifies a dysfunctional enhancer linked to IRF8 expression through CRISPRa screening and shows its regulation by a lncRNA and DNA methylation.

bioRxiv · Jun 11, 2021 · PreprintGenetics

SLE non-coding Genetic Risk Variant Determines the Epigenetic Dysfunction of an Immune Cell Specific Enhancer that Controls Disease-critical microRNA Expression

Guojun Hou, Isaac T. W. Harley, Xiaoming Lu, Tian Zhou, Ning Xu, Chao Yao, Yuting Qin, Ye Ouyang, Jianyang Ma, Xinyi Zhu, Xiang Yu, Hong Xu, Dai Dai, Huihua Ding, Zhihua Yin, , Nan Shen

The paper identifies a non-coding genetic variant associated with SLE that regulates miR-146a expression through a cell-type specific enhancer.

Nature Communications · Jan 8, 2021Peer-reviewedGenetics