NeuroscienceCell stem cellPeer-reviewed
Increased Cholesterol Synthesis Drives Neurotoxicity in Patient Stem Cell-Derived Model of Multiple Sclerosis
Rosana-Bristena Ionescu, Alexandra M. Nicaise, Julie A. Reisz…·Stefano Pluchino
This study identifies increased cholesterol synthesis in PMS patient-derived neural progenitor cells as a driver of neurotoxicity, which can be mitigated by simvastatin.
34 citationstop 1%