NeuroscienceAlzheimer s & DementiaPeer-reviewed
Nanoscale imaging of pT217-tau in aged rhesus macaque entorhinal and dorsolateral prefrontal cortex: Evidence of interneuronal trafficking and early-stage neurodegeneration
Dibyadeep Datta, Isabella Perone, Denethi Wijegunawardana…·Amy F.T. Arnsten
The paper examines pT217-tau localization in aged rhesus macaques, showing its aggregation on microtubules and trafficking between neurons, supporting its role as a fluid biomarker for early neurodegeneration.