Author

Denethi Wijegunawardana

Yale UniversityORCID 0000-0003-2103-5969Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Alvaro DuqueiD· 1 shared Amy F.T. ArnsteniD· 1 shared Austin M. VeireiD· 1 shared Christopher H. van DyckiD· 1 shared Dibyadeep DattaiD· 1 shared Feng LiangiD· 1 shared Isabella PeroneiD· 1 shared Jeffrey ZhouiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Alvaro DuqueORCID

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2 papers

Recent·Most cited

NeuroscienceNature NeurosciencePeer-reviewedAug 11, 2025

Aberrant splicing exonizes C9ORF72 repeat expansion in ALS/FTD

Suzhou Yang, Denethi Wijegunawardana, Udit Sheth…·Junjie U. Guo

The paper shows that C9ORF72 repeat expansions cause aberrant splicing, leading to exonization and altered RNA processing in ALS/FTD.

16 citationstop 1%

humanbulk RNA-seq

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NeuroscienceAlzheimer s & DementiaPeer-reviewedMar 6, 2024

Nanoscale imaging of pT217-tau in aged rhesus macaque entorhinal and dorsolateral prefrontal cortex: Evidence of interneuronal trafficking and early-stage neurodegeneration

Dibyadeep Datta, Isabella Perone, Denethi Wijegunawardana…·Amy F.T. Arnsten

The paper examines pT217-tau localization in aged rhesus macaques, showing its aggregation on microtubules and trafficking between neurons, supporting its role as a fluid biomarker for early neurodegeneration.

26 citationstop 2%

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