Author

Nai‐Ying Zheng

Weill Cornell MedicineORCID 0009-0005-8201-2623Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Chloe A. TroxelliD· 2 shared Jordan C. CherviniD· 2 shared Lei LiiD· 2 shared Min Huang· 2 shared Patrick C. WilsoniD· 2 shared Siriruk ChangrobiD· 2 shared Yanbin FuiD· 2 shared Atsuhiro YasuharaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersImmunology

Chloe A. TroxellORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 5, 2025

In Vivo Evolution of Monoclonal Antibody CR3022 to Achieve Cross-Neutralization of SARS-CoV-2 and Implications for Vaccine Strategies Against SARS-Related Viruses

Yanbin Fu, Ziqi Feng, Steven A. Erickson…·Patrick C. Wilson

This study shows that CR3022-like antibodies can be evolved in vivo through vaccination to neutralize SARS-CoV-2 and related viruses by enhancing affinity and breadth.

DOI 10.1101/2025.08.05.666673

humanexperimental assay

𝕏 PostBluesky

ImmunologyMolecular CellPeer-reviewedDec 20, 2024

Mutability and hypermutation antagonize immunoglobulin codon optimality

Joshua J.C. McGrath, Juyeon Park, Chloe A. Troxell…·Patrick C. Wilson

The paper examines how immunoglobulin codon optimality interacts with mutability and hypermutation in antibody evolution, finding that codon deoptimization correlates with expression loss and is constrained by selective pressures.

7 citations

humanmouse

𝕏 PostBluesky