Jonathan Anns

The paper introduces DABEST 2.0, an estimation framework for multi-group comparisons in experimental science, focusing on effect-size quantification instead of null-hypothesis significance testing.

The paper tests optoGPCRs in Drosophila, finding MosOPN3 provides effective, low-toxicity inhibition with brief light pulses.

This study evaluates kalium channelrhodopsins (KCRs) as optogenetic inhibitors in Drosophila, C. elegans, and zebrafish, showing they are effective and have improved properties compared to chloride-conducting ACRs.