Yishan Mai

The paper introduces DABEST 2.0, an estimation framework for multi-group comparisons in experimental science, focusing on effect-size quantification instead of null-hypothesis significance testing.

The paper introduces a long-Stokes-shift mScarlet variant for two-photon imaging, enabling simultaneous imaging with green sensors using a single laser.

The paper tests optoGPCRs in Drosophila, finding MosOPN3 provides effective, low-toxicity inhibition with brief light pulses.

The paper shows that optogenetic activation of sensory and dopaminergic neurons can induce synthetic associative memories in vinegar flies, demonstrating that simple coincident stimulation is sufficient for memory formation.

The paper evaluates Nav1.8 as a therapeutic target for Pitt Hopkins Syndrome by reviewing literature and presenting data showing its inhibition normalizes neuron function and behavior in mouse models.

The paper identifies a distinct population of hippocampal neurons projecting to the prelimbic cortex that regulate context fear memory recall through molecular and circuit-specific mechanisms.

The paper identifies Bdnf promoter IV-expressing cells in the hippocampus and shows their role in fear expression and hippocampal-prefrontal synchrony in mice.