Author

Huazhang Shu

Science for Life LaboratoryORCID 0009-0005-8911-952XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

André B. P. KuilenburgiD· 1 shared Andrei ChabesiD· 1 shared Elisabetta Boeri ErbaiD· 1 shared Lilian Frank· 1 shared Magnus Nørregaard GrønsetiD· 1 shared Margaux MolinasiD· 1 shared Margot WeberiD· 1 shared Marianna TampereiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

André B. P. KuilenburgORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedNov 26, 2025

Structural basis for human chondroitin sulfate chain polymerization

Poushalee Dutta, R.L. Cordeiro, Mélanie Friedel-Arboleas…·Rebekka Wild

This study identifies four heterodimeric complexes involved in human chondroitin sulfate chain polymerization and proposes a non-processive, disruptive mechanism based on structural and functional analyses.

5 citations

humanexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintMay 13, 2025

Uridine cytidine kinases dictate the therapeutic response of molnupiravir via its bioactivation

Huazhang Shu, Sushma Sharma, Seher Alam…·Si Min Zhang

This study identifies uridine cytidine kinases (UCKs) as key enzymes that phosphorylate molnupiravir's active metabolite, influencing its antiviral efficacy and selectivity against SARS-CoV-2.

DOI 10.1101/2025.05.13.653844

humanexperimental assay

𝕏 PostBluesky