Author

André B. P. Kuilenburg

Amsterdam University Medical CentersORCID 0000-0002-7989-4910Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrei ChabesiD· 1 shared Arjan BoltjesiD· 1 shared Bruce E. Hayward· 1 shared C. Pita Barros· 1 shared Carlijn VoermansiD· 1 shared Caroline HochheuseriD· 1 shared Clara van KarnebeekiD· 1 shared Daman KumariiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

Andrei ChabesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Metastatic tumor cells in bone marrow differ from paired neuroblastoma tumor and contain subsets with therapy-resistant characteristics

Caroline Hochheuser, Arjan Boltjes, K. M. Keller, Simon Tol, M. van de Mheen, C. Pita Barros, Zeinab van Gestel-Fadaie, A. B. P. van Kuilenburg, Sander R. van Hooff, Carlijn Voermans, Jan J. Molenaar, Godelieve A.M. Tytgat, Ilse Timmerman

EJC Paediatric Oncology · Mar 25, 2026Peer-reviewedCancer Biology

Uridine cytidine kinases dictate the therapeutic response of molnupiravir via its bioactivation

Huazhang Shu, Sushma Sharma, Seher Alam, Lilian Frank, Marianna Tampere, André B. P. Kuilenburg, Nicholas C.K. Valerie, Mikael Altun, Andrei Chabes, Sean G. Rudd, Si Min Zhang

This study identifies uridine cytidine kinases (UCKs) as key enzymes that phosphorylate molnupiravir's active metabolite, influencing its antiviral efficacy and selectivity against SARS-CoV-2.

bioRxiv · May 13, 2025 · PreprintMicrobiology

All three MutL complexes are required for repeat expansion in a human stem cell model of CAG-repeat expansion mediated glutaminase deficiency.

Bruce E. Hayward, Daman Kumari, Saikat Santra, Clara van Karnebeek, André B. P. Kuilenburg, Karen Usdin

Scientific Reports · Jun 14, 2024Peer-reviewedGenetics