Ilona Szczot

The paper shows that TRPV1+ afferents rapidly reprogram TRPV1- Aβ afferents, leading to hyperalgesia in humans.

The paper maps nociceptive signaling architecture by combining activity labeling with single-cell RNA sequencing, revealing a hierarchical organization of mechano-nociceptor populations based on tissue domain and organ context.

This study investigates the neural basis of touch pleasantness by comparing two motion conditions and finds that velocity tuning of pleasantness is not solely dependent on peripheral C-LTMRs.

The paper identifies PIEZO2-dependent mechanical pain in humans and mice, showing hair-pull pain is mediated by Aβ inputs and specific nociceptors.