Cell BiologyNature CommunicationsPeer-reviewed
Membrane lipid poly-unsaturation selectively affects dopamine D2 receptor internalization
Silvia Sposini, Rim Baccouch, Mathias Lescuyer…·Isabel D. Alves
This study shows that membrane poly-unsaturated fatty acids (PUFAs) impair dopamine D2 receptor (D2R) endocytosis without affecting other GPCRs or clathrin-mediated endocytosis.
DOI 10.1038/s41467-026-73057-5