Cell BiologyNucleic Acids ResearchPeer-reviewed
Mrx6 binds the Lon protease Pim1 N-terminal domain to confer selective substrate specificity and regulate mtDNA copy number
Simon Schrott, Ilaria Marafelli, Charlotte Gerle…·Christof Osman
This study identifies Mrx6's role in regulating mtDNA copy number through its interaction with Pim1 and Mam33, revealing a mechanism involving substrate specificity and protein stability.
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