Author

Karyn E. King

University of OttawaORCID 0009-0006-4178-4392Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Maxime W.C. RousseauxiD· 2 shared Ryan Charles RusselliD· 2 shared Truc T. LosieriD· 2 shared J. Taylor· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersGenomics

Maxime W.C. RousseauxORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 11, 2026

A Pooled CRISPR Screen Protocol for Comparative Pathway Analysis Across Multiple Stressors

Truc T. Losier, Karyn E. King, J. Taylor…·Ryan Charles Russell

This paper introduces a refined CRISPR screening protocol to compare cellular responses across multiple stressors, reducing false positives by 40% through fluorescence-based reporters and fixation steps.

DOI 10.64898/2026.09.07.749902

CRISPR screenexperimental assay

𝕏 PostBluesky

Cell BiologyThe Journal of Cell BiologyPeer-reviewedJun 24, 2025

Identification of stress specific autophagy regulators from tandem CRISPR screens

Truc T. Losier, Karyn E. King, Maxime W.C. Rousseaux, Ryan Charles Russell

The paper identifies stress-specific autophagy regulators using CRISPR screens, finding unique kinases for ER-phagy and pexophagy.

5 citations

humangenetic perturbation / CRISPR

𝕏 PostBluesky