Author

Michael D. Brodt

Washington University in St. LouisORCID 0009-0006-6901-2490Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Christopher J. Chermside‐ScabboiD· 2 shared Lisa Y. LawsoniD· 2 shared Matthew J. SilvaiD· 2 shared Nicole MigotskyiD· 2 shared Evan G. BuettmanniD· 1 shared John T. ShusteriD· 1 shared Ramya Palaniappan· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 19 mutual co-author links

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2 shared papersPhysiology

Christopher J. Chermside‐ScabboORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintFeb 24, 2026

Combination Treatment with Sclerostin and Dkk1 Antibodies Synergizes with Tibial Loading to Stimulate Bone Formation in Aged Mice

Lisa Y. Lawson, Christopher J. Chermside‐Scabbo, Michael D. Brodt…·Matthew J. Silva

This study shows that combining Sclerostin and Dkk1 antibodies with mechanical loading significantly enhances bone formation in aged mice.

DOI 10.64898/2026.02.23.707532

mouseexperimental assay

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GeneticsJournal of Bone and Mineral ResearchPeer-reviewedDec 1, 2020

Osteoblast-Specific Wnt Secretion is Required for Skeletal Homeostasis and Loading-Induced Bone Formation in Adult Mice

Lisa Y. Lawson, Michael D. Brodt, Nicole Migotsky…·Matthew J. Silva

This study shows that osteoblast-specific Wnt secretion is essential for maintaining bone homeostasis and the anabolic response to mechanical loading in adult mice.

42 citations

mouseexperimental assay

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