Pharmacology & ToxicologyJournal of Medicinal ChemistryPeer-reviewed
A fluorescent probe enables the discovery of improved antagonists targeting the intracellular allosteric site of the chemokine receptor CCR7
Silas L. Wurnig, Max E. Huber, Corinna Weiler…·Finn K. Hansen
This study develops a fluorescent ligand to identify improved antagonists targeting the intracellular allosteric site of CCR7, showing their effectiveness in both recombinant and endogenous settings.