Author

Francisca Díaz-Tejeda

Austral University of ChileORCID 0009-0007-0348-6893Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Guillermo ValenzuelaiD· 2 shared Alejandro Rojas‐FernándeziD· 1 shared Catalina Méndez· 1 shared Claudio Cappelli Leon· 1 shared Constanza Salinas-RebolledoiD· 1 shared Consuelo Jalife· 1 shared Cristian MontecinosiD· 1 shared David A. Brown‐Brown· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Guillermo ValenzuelaORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 5, 2026

RNA-DNA triplex-forming miRNAs define an evolutionarily recent chromatin regulatory mechanism

Michell Martin, Consuelo Jalife, Catalina Méndez…·R. Maldonado

The paper identifies RNA-DNA triplex-forming miRNAs in human cells and shows they are evolutionarily recent and associated with Ago2-chromatin interactions.

DOI 10.64898/2026.02.25.707792

humanbulk RNA-seq

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BiochemistryeLifePeer-reviewedNov 25, 2025

Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (PROTAC)

Constanza Salinas-Rebolledo, Javier Blesa, Guillermo Valenzuela…·Alejandro Rojas‐Fernández

This paper describes the engineering of a PROTAC that uses p97-directed proteolysis to achieve specific substrate degradation without relying on E3 ubiquitin ligases.

3 citations

proteomicsexperimental assay

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