Author

Kassandra J. Naughton

University of KentuckyORCID 0009-0007-0400-0066Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

Avery R. ChildressiD· 2 shared Christian M. GosseriD· 2 shared Christine F. BrainsoniD· 2 shared Daniel R. PlaugheriD· 2 shared Dave-Preston I. Esoe· 2 shared Erika M. SkaggsiD· 2 shared Jinpeng LiuiD· 2 shared Ryan A. GoettliD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Avery R. ChildressORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 1, 2026

EZH1/2 inhibition improves immunotherapy response through MHC Class II de-repression and neutrophil reprogramming

Avery R. Childress, Dave-Preston I. Esoe, Xiulong Song…·Christine F. Brainson

This study shows that EZH1/2 inhibition with valemetostat enhances anti-PD1 immunotherapy in lung squamous cell carcinoma by increasing MHC Class II and reprogramming neutrophils.

DOI 10.64898/2026.06.01.725956

mouseproteomics

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Cancer BiologybioRxivPreprintJun 25, 2024

Methionine Restriction Reduces Lung Cancer Progression and Increases Chemotherapy Response

Kassandra J. Naughton, Xiulong Song, Avery R. Childress…·Christine F. Brainson

This study shows that methionine restriction reduces lung cancer progression and enhances chemotherapy response in a mouse model and human cell lines.

5 citations

mouseproteomics

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