Kaelin Sbrocco

This study investigates how cerebellar dysfunction in SCA1 affects prefrontal cortex function and cognition, finding that cerebellar degeneration can both impair and ameliorate PFC dysfunction depending on disease context.

This study examines spatiotemporal changes in astrocyte phenotypes in SCA1 mice, finding region-specific alterations in astrocyte function and homeostasis that may contribute to disease progression.