DIALECT: DNA-Programmable Synthetic Cells Communicate with Mammalian Cells through Synthetic Receptors
Jesse Lentjes, Anna-Maria Makri-Pistikou, Bas W. A. Bogels, Maaruthy Yelleswarapu, Shuo Yang, Alexander Grawe, Thijs W. van Veldhuisen, Federica Eduati, Maarten Merkx, Jan C. M. van Hest, Stephen Mann, Tom F. A. de Greef
DIALECT enables synthetic cells to communicate with mammalian cells via DNA-programmed ligand release and engineered receptors, achieving specific signaling and logic gate functions.
bioRxiv · Nov 9, 2026 · PreprintSynthetic Biology