Kari A. Koppitch

The paper demonstrates that human nephron cells can switch between proximal and distal identities through WNT, FGF, and BMP signaling, showing developmental plasticity.

The paper compares single-cell chromatin and gene expression data from human and mouse kidney development to identify conserved and divergent features and human-specific enhancer regions linked to kidney disease.

The paper uses spatial transcriptomics to identify injury-specific microenvironments and molecular interactions in the mouse kidney during injury and regeneration.

The paper identifies androgen receptor-mediated regulation of sexually dimorphic gene expression in the mouse kidney and finds limited conservation in human kidney.